Three months later, during the Battle of Arcadia, the ship was tasked with retrieving a log buoy dropped by UNSC Spirit of Fire and to avoid combat, as Arcadia was deemed a lost cause. However, in a fit of pride, Hood attempted to take revenge for all the fallen colonies and ordered the crew to attack the CPV-class heavy destroyer Radiant Perception. Roman Blue was outmatched and forced to retreat without retrieving the log, thus leaving no chance of rescue for Spirit of Fire and her crew. Following the mission failure, Hood was transferred to the support frigate UNSC Burlington, with command of the Roman Blue being handed over to Captain William Webb.
In 2535, the Roman Blue was part of Vice Admiral Jean Mawikizi's fleet formed to protect Chi Rho when it became clear the Covenant were close to finding it. During the battle, the Roman Blue was cut in half by an energy beam and its front quarter crashed on the moon Eiro. The crash site was found in January 2557 by Rion Forge and her team of scavengers.