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After the UNSC Callisto was captured by Insurrectionists, the UNSC sent the UNSC Las Vegas, the UNSC Jericho, and the UNSC Buenos Aires warships to hunt it down. The ships' crews were completely inexperienced, and had never fired their weapons in combat before. Thus, they where unprepared for launching rockets without observation.
On March 2, 2494, they encountered the Callisto in the 26 Draconis system. The three UNSC ships fired six of their seven Ares missiles, and in response, the now Insurrectionist-controlled ship maneuvered behind an asteroid, which it then detonated in the direction of the UNSC vessels using a nuclear warhead planted beforehand. The Las Vegas was seriously damaged, and Lewis along with many others where killed by the explosion, along with nearly all of the bridge crew and anyone else caught within the blast radius.