First Strike may refer to the following:
- Halo: First Strike - The book written by Eric Nylund.
- Operation: FIRST STRIKE - The UNSC raid that destroyed almost all of a Covenant armada.
- First Strike Medal - A medal awarded in Halo: Reach for getting the first kill of the game.
- This is a disambiguation page - a navigational aid which lists other pages that might otherwise share the same title. If an article link referred you here, you might want to go back and fix it to point directly to the intended page.